Executive Summary

The global protein expression market is expected to reach USD 4.1 billion by 2025, growing at a CAGR of 11.3% from 2020 to 2025. The market is primarily driven by the increasing demand for biologics, rising R&D funding, and technological advancements in the field of protein expression. The market is also expected to witness significant growth in emerging economies, such as Asia-Pacific and Latin America, due to the increasing focus on healthcare infrastructure and research activities.

Important Note: The companies listed in the image above are for reference only. The final study will cover 18–20 key players in this market, and the list can be adjusted based on our client’s requirements.

Key Market Insights

The global protein expression market is driven by various factors, including the increasing demand for biologics, rising R&D funding, and technological advancements in the field of protein expression. The market is also witnessing significant growth in emerging economies, such as Asia-Pacific and Latin America, due to the increasing focus on healthcare infrastructure and research activities.

Market Drivers

The increasing demand for biologics is a key driver of the protein expression market. Biologics are complex molecules, such as proteins, peptides, and antibodies, that are used for the treatment of various diseases, such as cancer, autoimmune disorders, and infectious diseases. The use of biologics has increased significantly in recent years, owing to their higher efficacy and specificity compared to traditional small molecule drugs.

Another driver of the protein expression market is the rising R&D funding. Governments and private organizations are investing heavily in research and development activities to discover new therapies and drugs for various diseases. This has led to a significant increase in the demand for protein expression technologies and services.

Technological advancements in the field of protein expression are also driving the market growth. The development of high-throughput and automated technologies has significantly improved the efficiency and speed of protein expression. The introduction of advanced expression vectors, such as baculovirus and mammalian vectors, has also increased the yield and quality of recombinant proteins.

Market Restraints

Despite the growth prospects, the protein expression market is also facing certain challenges that could restrain market growth. The high cost of protein expression technologies and services is one of the major challenges faced by the market. The lack of skilled personnel is another significant challenge, which is hindering the adoption of protein expression technologies and services.

Market Opportunities

The protein expression market offers significant growth opportunities, driven by the increasing demand for biologics, rising R&D funding, and technological advancements in the field of protein expression. The market is also expected to witness significant growth in emerging economies, such as Asia-Pacific and Latin America, due to the increasing focus on healthcare infrastructure and research activities.

Market Dynamics

The protein expression market is highly dynamic and is influenced by various factors, such as technological advancements, changing regulatory environment, and market trends. The market is also highly competitive, with several key players operating in the market. The market players are focusing on strategic partnerships, collaborations, and acquisitions to expand their market presence and product portfolio.

Regional Analysis

The global protein expression market is segmented into North America, Europe, Asia-Pacific, Latin America, and the Middle East & Africa. North America dominated the market in 2019, owing to the increasing demand for biologics and the presence of key market players. However, the Asia-Pacific region is expected to witness significant growth during the forecast period, driven by the increasing focus on healthcare infrastructure and research activities in emerging economies, such as India and China.

Competitive Landscape

Leading companies in the Protein Expression market:

1. Thermo Fisher Scientific Inc.
2. Merck KGaA (EMD Millipore)
3. GenScript Biotech Corporation
4. Takara Bio Inc.
5. Lonza Group Ltd.
6. Agilent Technologies, Inc.
7. QIAGEN N.V.
8. Promega Corporation
9. Bio-Rad Laboratories, Inc.
10. Oxford Expression Technologies Ltd.

Please note: This is a preliminary list; the final study will feature 18–20 leading companies in this market. The selection of companies in the final report can be customized based on our client’s specific requirements.

Segmentation

The global protein expression market is segmented into expression systems, products and services, applications, and end-users.

By expression systems, the market is segmented into prokaryotic expression systems, mammalian expression systems, insect expression systems, yeast expression systems, and other expression systems.

By products and services, the market is segmented into expression vectors, reagents, competent cells, instruments, services, and other products and services.

By applications, the market is segmented into therapeutic applications, research applications, and industrial applications.

By end-users, the market is segmented into pharmaceutical and biotechnology companies, academic research institutes, and contract research organizations.

Category-wise Insights

By expression systems, the mammalian expression systems segment dominated the market in 2019, owing to their high yield and quality of recombinant proteins. The prokaryotic expression systems segment is also expected to witness significant growth during the forecast period, owing to their low cost and ease of use.

By products and services, the expression vectors segment dominated the market in 2019, owing to their high demand in protein expression applications. The services segment is also expected to witness significant growth during the forecast period, driven by the increasing outsourcing of protein expression services by pharmaceutical and biotechnology companies.

By applications, the therapeutic applications segment dominated the market in 2019, owing to the increasing demand for biologics for the treatment of various diseases. The research applications segment is also expected to witness significant growth during the forecast period, driven by the increasing research activities in the field of protein expression.

By end-users, the pharmaceutical and biotechnology companies segment dominated the market in 2019, owing to the high demand for biologics for therapeutic applications. The academic research institutes segment is also expected to witness significant growth during the forecast period, driven by the increasing research activities in the field of protein expression.

Key Benefits for Industry Participants and Stakeholders

The protein expression market offers several benefits for industry participants and stakeholders, including:

• Growing demand for biologics, offering significant growth opportunities for the market players
• Increasing R&D funding, leading to the development of new protein expression technologies and services
• Technological advancements in the field of protein expression, improving the efficiency and speed of protein expression
• Rising outsourcing of protein expression services, offering new revenue streams for contract research organizations

SWOT Analysis

Strengths:

• Growing demand for biologics, offering significant growth opportunities for the market players
• Technological advancements in the field of protein expression, improving the efficiency and speed of protein expression

Weaknesses:

• High cost of protein expression technologies and services, limiting their adoption
• Lack of skilled personnel, hindering the adoption of protein expression technologies and services

Opportunities:

• Increasing R&D funding, leading to the development of new protein expression technologies and services
• Rising demand for biologics in emerging economies, such as Asia-Pacific and Latin America
• Growing outsourcing of protein expression services, offering new revenue streams for contract research organizations

Threats:

• Stringent regulatory requirements, increasing the time and cost of protein expression research and development
• Competition from alternative technologies, such as cell-free protein expression and in vitro transcription/translation systems

Market Key Trends

The protein expression market is witnessing several key trends that are shaping the market landscape, including:

• Increasing demand for biologics for therapeutic applications
• Rising adoption of advanced expression vectors, such as baculovirus and mammalian vectors
• Growing focus on research activities in emerging economies, such as India and China
• Increasing outsourcing of protein expression services by pharmaceutical and biotechnology companies
• Technological advancements in the field of protein expression, improving the efficiency and speed of protein expression

Covid-19 Impact

The Covid-19 pandemic has had a significant impact on the protein expression market, with the rising demand for biologics and vaccines for the treatment and prevention of the virus. The pandemic has also led to increased funding for research and development activities, driving the growth of the protein expression market. However, the pandemic has also resulted in supply chain disruptions and delays in clinical trials, which have impacted the market growth to some extent.

Key Industry Developments

The protein expression market has witnessed several key industry developments in recent years, including:

• In March 2021, Lonza Group Ltd. announced the launch of its new GS Xceed expression system, which is designed to improve the yield and quality of recombinant proteins.
• In October 2020, Thermo Fisher Scientific, Inc. announced the acquisition of QIAGEN N.V., a leading provider of sample and assay technologies for molecular diagnostics and life sciences.
• In June 2020, Merck KGaA announced the launch of its new Mobius® MyWay portfolio of bioprocessing equipment, which is designed to improve the efficiency and scalability of protein expression processes.

Analyst Suggestions

The protein expression market is expected to witness significant growth during the forecast period, driven by the increasing demand for biologics, rising R&D funding, and technological advancements in the field of protein expression. The market players are advised to focus on strategic partnerships, collaborations, and acquisitions to expand their market presence and product portfolio. The market players should also invest in research and development activities to discover new therapies and drugs for various diseases.

Future Outlook

The protein expression market is expected to witness significant growth during the forecast period, driven by the increasing demand for biologics, rising R&D funding, and technological advancements in the field of protein expression. The market is also expected to witness significant growth in emerging economies, such as Asia-Pacific and Latin America, due to the increasing focus on healthcare infrastructure and research activities.

However, the market is also facing certain challenges, such as the high cost of protein expression technologies and services and the lack of skilled personnel, which could restrain market growth to some extent.

Conclusion

The protein expression market is a rapidly growing market, driven by the increasing demand for biologics, rising R&D funding, and technological advancements in the field of protein expression. The market is also witnessing significant growth in emerging economies, such as Asia-Pacific and Latin America, due to the increasing focus on healthcare infrastructure and research activities. However, the market is also facing certain challenges, such as the high cost of protein expression technologies and services and the lack of skilled personnel, which could restrain market growth to some extent.