Knee Cartilage Replacement Market 2023
knee cartilage replacement surgery’s goal is to replace the worn-out cartilage in the knee with fresh, healthy material. Microfracture surgery or cartilage resurfacing are other names for this procedure. A joint that is continuously moving and put under a lot of stress is the knee. This deterioration over time can result in arthritis, a degenerative condition that causes the cartilage in the knee to deteriorate. When this occurs, the knee joint may become extremely painful and stiff.
The function of the knee joint can be recovered after surgery to replace the knee cartilage. Small incisions are made in the knee during this procedure, and fresh cartilage is subsequently inserted into the joint. The knee joint will be softer and more mobile thanks to the new cartilage. Patients who have arthritis or who have had their knee cartilage damaged by an injury frequently undergo knee cartilage replacement surgery. The pain caused by these disorders may be effectively treated with this surgery, which may also help the knee joint function better.
It’s crucial to discuss the advantages and disadvantages of knee replacement surgery with your doctor if you’re thinking about having it done. Not everyone should undergo this procedure, and your doctor can advise you on whether it is the best course of action for you.
What exactly is knee cartilage replacement?
The complicated hinge joint in the knee enables the leg to bend and straighten. The femur, which is the lower end of the thighbone, fits into the trough, which is the top end of the shinbone, to form the knee joint (tibia). Articular cartilage, a smooth tissue, covers the knee joint. The bones may move easily over one another thanks to the low-friction surface provided by this cartilage.
The patellae, two little circular bones that sit in front of the knee joint, are also present. The quadriceps tendon, a robust band of tissue, joins the patella to the femur. The patella, which the quadriceps tendon joins, is attached to the tibia by the patellar ligament.
A multitude of powerful ligaments hold the knee joint together. On the sides of the knee joint, there are two collateral ligaments that support and stabilise the joint. On the inside of the knee joint is the medial collateral ligament, and on the outside is the lateral collateral ligament.
The anterior cruciate ligament (ACL), which connects the front of the femur to the rear of the tibia, is situated in the middle of the knee joint. The ACL aids in knee joint stabilisation and stops the tibia from sliding in front of the femur.
The posterior cruciate ligament (PCL), which spans from the rear of the femur to the front of the tibia, is situated in the middle of the knee joint. The PCL aids in knee joint stabilisation and stops the tibia from moving in front of the femur.
Numerous muscles and tendons surround the knee joint, which aid in the joint’s movement. The quadriceps muscles attach to the patella and are situated in the front of the thigh. At the knee, the quadriceps muscles straighten the leg.
Knee Cartilage Replacement Market Report Scope and Segmentation
|UNIT||Value (USD Million/Billion)|
|BY REGION||North America, Europe, Asia Pacific, Latin America, Middle East and Africa|
Overview of the Knee Cartilage Replacement Market
The global market for knee cartilage replacement is anticipated to reach US$ 2,727.1 million by 2026, at a CAGR of 5.6% over the forecast period, according to a new market research analysis from MWR (2018–2026). The most prevalent kind of arthritis, osteoarthritis, is becoming more and more widespread, and this is what is essentially driving the knee cartilage replacement business. Around 27 million people in the US suffer from osteoarthritis, which is the main cause of knee pain.
Another significant driver propelling the expansion of the knee cartilage replacement market is the growing elderly population. The need for knee cartilage replacement surgeries is anticipated to increase since the older population is more susceptible to osteoarthritis and other degenerative disorders. The market for knee cartilage replacements is also anticipated to rise as a result of the rising frequency of sports injuries.
The treatment type, end-user, and geographic segments have been used to divide the global market for knee cartilage replacement. Allogeneic knee cartilage replacement, autologous knee cartilage replacement, and other procedures have been classified as different technique types on the market. During the projected period, the allogeneic knee cartilage replacement segment is anticipated to develop at the greatest CAGR.
The global market for knee cartilage replacement has been segmented according to end-user into hospitals, ambulatory surgical centres, and others. During the projection period, it is anticipated that the hospital sector will increase at the greatest CAGR.
Five primary regions have been used to segment the global knee cartilage replacement market: North America, Europe, Asia Pacific, Latin America, and the Middle East and Africa. Due to the increased prevalence of osteoarthritis, the presence of numerous hospitals and ambulatory surgical centres, and the accessibility of cutting-edge medical facilities, North America is predicted to lead the global knee cartilage replacement market.
Asia-Pacific is expected to experience the fastest growth.
Market Development for Knee Cartilage Replacement
In the upcoming ten years, the market for knee cartilage replacement is anticipated to expand dramatically. This is brought on by the rise in people with knee osteoarthritis, a degenerative joint condition that causes cartilage to deteriorate. By 2030, 67 million people are anticipated to have knee osteoarthritis, according to the World Health Organization.
In a surgical technique called knee cartilage replacement, artificial cartilage is used to replace the damaged cartilage. This surgery has the potential to lessen knee discomfort and enhance knee joint performance. Autologous chondrocyte implantation (ACI) and allogeneic chondrocyte implantation (AlloCi) are the two primary procedures used to restore knee cartilage.
ACI is a process in which the patient’s own healthy cartilage cells are removed and placed in the injured area. In the AlloCi treatment, healthy cartilage cells from a donor are removed and then injected into the injured area.
The market for knee cartilage replacement is anticipated to grow as a result of a number of factors, including the rising incidence of knee osteoarthritis, the availability of new and better surgical methods, and the rising number of hospitals and clinics that perform knee cartilage replacement surgery.
Procedure, end-user, and region are the main segments of the knee cartilage replacement market.
The knee cartilage replacement market is divided into allogeneic chondrocyte implantation (AlloCi), autologous chondrocyte implantation (ACI), and others based on the procedure.
The knee cartilage replacement market is divided into hospitals, ambulatory surgical facilities, and others based on end-user.
The knee cartilage replacement market is divided into five regions based on geography: North America, Europe, Asia Pacific, Latin America, and the Middle East and Africa.
Zimmer Biomet, Stryker, Smith & Nephew, DePuy Synthes, and B. Braun are the leading companies in the knee cartilage replacement market.
Regional Analysis of the Knee Cartilage Replacement Market
From 2020 to 2025, the global market for knee cartilage replacement is expected to grow at a compound annual growth rate (CAGR) of about 5.5%. One of the main elements fueling the market’s expansion is the rise in sports injuries. The National Athletic Trainers’ Association estimates that each year in the US, 4 million high school and university players experience a sports-related injury. Furthermore, one of the key drivers fueling the market’s expansion is the rising percentage of obese people in society. The World Health Organization (WHO) estimates that in 2016, around 1.9 billion persons aged 18 and older were overweight, with 650 million of them being obese. Osteoarthritis, the most prevalent form of arthritis, is greatly increased by obesity.
During the projected period, North America is anticipated to account for the biggest market share. A significant portion is related to the region’s growing obesity problem and the increase in sports injuries. The National Athletic Trainers’ Association estimates that each year in the US, 4 million high school and university players experience a sports-related injury. In addition, the National Institutes of Health estimate that in the US, 93.3 million adults were obese in 2015–2016.
Because of the region’s ageing population and increased rate of sports injuries, the Asia-Pacific region is expected to grow the fastest during the projection period. The Department of Economic and Social Affairs of the United Nations projects that by 2050, there will be 1.3 billion elderly people living in Asia. In addition, the National Athletic Trainers’ Association estimates that 300 million individuals in China participate in sports or other physical activities.
Zimmer Biomet, DePuy Synthes Companies, Stryker, Smith & Nephew, and Integra LifeSciences are a few of the key companies in the market.
Market Challenges for Knee Cartilage Replacement
During the forecast period of 2019–2026, the global knee cartilage replacement market is anticipated to expand at a CAGR of about 4.5%. The two main reasons propelling the market’s expansion are the increased incidence of osteoarthritis and the rise in sports-related injuries.
However, the biggest obstacles impeding the market’s growth are the high cost of knee cartilage replacement surgery and the danger of complications from the procedure.
The most prevalent type of arthritis, osteoarthritis, is a degenerative condition that affects the joints. It is characterised by cartilage disintegration, which causes joint discomfort, stiffness, and edema. The Centers for Disease Control and Prevention (CDC) estimate that 54.4 million people in the US have arthritis of some kind.
Another significant element fueling the expansion of the knee cartilage replacement market is the increase in injuries sustained while participating in sports. The National Athletic Trainers’ Association estimates that each year in the US, 2.6 million athletes experience a sports-related injury.
The high price of knee cartilage replacement surgery is a significant obstacle impeding the market’s expansion. The cost of the procedure, which can range from $15,000 to $30,000, is typically not covered by insurance.
Another significant difficulty is the possibility of problems following knee cartilage replacement surgery. Infection, blood clots, and nerve damage are the most typical side effects.
Impact of the Knee Cartilage Replacement Market (Covid-19)
The market for knee cartilage replacements has been significantly impacted by the novel coronavirus (COVID-19) epidemic. The pandemic has pushed hospitals and orthopedic clinics all around the world to postpone or cancel elective surgery, which has decreased demand for knee cartilage replacement goods. Additionally, because many manufacturers are situated in China and other pandemic-affected nations, border closures and travel restrictions have hindered the supply of knee cartilage replacement supplies.
With a compound annual growth rate (CAGR) of -15.5%, the knee cartilage replacement industry, which was valued at $3.9 billion in 2019, is predicted to drop to $3.3 billion in 2020. At a CAGR of 5.7%, the market is anticipated to rebound and increase to $4.4 billion by 2023.
The COVID-19 pandemic is the main cause of the reduction in the market for knee cartilage replacement. Due to the pandemic, hospitals and orthopedic clinics all around the world have delayed or cancelled elective surgeries, which has decreased demand for knee cartilage replacement goods. Additionally, because many manufacturers are situated in China and other pandemic-affected nations, border closures and travel restrictions have hindered the supply of knee cartilage replacement supplies.
The market for knee cartilage replacement is divided into product, technique, end-user, and geographic segments.
The market is divided into allografts, autografts, and synthetic grafts based on the product.
The largest product category in 2019 was allografts, which accounted for 48.8% of the market. Patients with significant cartilage damage frequently use allografts, which are made from donor tissue.
With 45.3% of the market, autografts are the second-largest product category in 2019. Autografts are typically used in patients with less severe cartilage injuries because they are made from the patient’s own tissue.
The smallest product category in 2019 was synthetic grafts, which made up 5.9% of the market.
Key Industry Developments in the Knee Cartilage Replacement Market
During the projected period of 2020–2025, the market for replacement knee cartilage is anticipated to expand at a CAGR of about 6%. The rising elderly population, the incidence of osteoarthritis, and the increased desire for minimally invasive procedures are the main factors propelling the market’s expansion.
The World Health Organization (WHO) estimates that 10% of people around the world have osteoarthritis. Additionally, according to the WHO, 180 million people worldwide will have osteoarthritis by 2050. The slow deterioration of joint cartilage is a hallmark of osteoarthritis, a degenerative joint condition. It is a significant contributor to impairment in the ageing population. Osteoarthritis signs and symptoms include joint pain, stiffness, and edema.
One of the joints most frequently impacted by osteoarthritis is the knee. The cartilage in the knee joint may be entirely damaged in severe osteoarthritis cases. This may result in joint discomfort, edema, and deformity. Patients with advanced osteoarthritis of the knee can be treated surgically with knee cartilage replacement. In this surgery, artificial cartilage is used to replace the injured cartilage.
The two primary procedures for replacing knee cartilage are allograft surgery and autograft surgery. The artificial cartilage used in allograft surgery is created from donor tissue. The artificial cartilage used in autograft surgery is created from the patient’s own tissue. Knee replacement surgery is a significant procedure that is often carried out in a hospital.
Type, procedure, end-user, and geography are the segments used to categories the global knee cartilage replacement market.
The market is divided into allograft surgery and autograft surgery based on kind. The CAGR for allograft surgery is predicted to be the highest over the projection period. This is brought on by the growing quantity of allograft transplant surgeries and the growing availability of donor tissue. According to the process, the market is divided into arthroscopic surgery and open surgery.
Conclusion for the Knee Cartilage Replacement Market
In the upcoming years, it is anticipated that the market for knee cartilage replacement will expand dramatically. This is explained by the increasing incidence of knee injuries and the increased demand for knee surgery.
MWR estimates that by 2026, the global market for knee cartilage replacement will be worth US$4.5 billion. From 2018 to 2026, the market is projected to grow at a CAGR of 7.4%.
Due to the high prevalence of knee injuries and the availability of cutting-edge treatment options, North America is predicted to have the largest market for knee cartilage replacement. Due to the rising senior population and increased awareness of knee cartilage replacement surgery, the market in Asia-Pacific is predicted to grow quickly.
Anika Therapeutics, Inc., Zimmer Biomet Holdings, Inc., Stryker Corporation, Smith & Nephew plc, and Integra LifeSciences Holdings Corporation are a few of the major companies in the global knee cartilage replacement industry.
- Anika Therapeutics
- EMD Serono Inc.
- Zimmer Biomet
- DePuy Synthes
- CellGenix GmbH
- Genzyme Corporation
|By Product||· Microfracture Devices|
· Osteochondral Dart
|By Cartilage Type||· Fibrocartilage|
· Hyaline Cartilage
|By Type of Cells||· Hospitals|
· Specialty Clinics
· Ambulatory Surgery Centers
|By Geography||· North America (USA and Canada)|
· Europe (UK, Germany, France, Italy, Spain, Scandinavia and Rest of Europe)
· Asia Pacific (Japan, China, India, Australia, Southeast Asia and Rest of Asia Pacific)
· Latin America (Brazil, Mexico and Rest of Latin America)
· Middle East & Africa (South Africa, GCC and Rest of Middle East & Africa)