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Ion Chromatography Market Analysis- Industry Size, Share, Research Report, Insights, Covid-19 Impact, Statistics, Trends, Growth and Forecast 2022-2030

Published Date: August, 2022
No of Pages: 168
Delivery Format: PDF+ Excel

$2,950.00

The global ion chromatography market is projected to be worth ~USD 3,794.96 million by 2027, registering a CAGR of ~8.51% during the forecast period (2021-2027). The market was valued at USD 2,325 million in 2020.

The ion chromatography market is driven by the increasing use of ion chromatography techniques for the process of protein purification, growing demand for monoclonal antibodies, and rising adoption of ion chromatography techniques in various applications such as food & beverage and pharmaceuticals. This is one of the major factors boosting the market growth. However, there are pitfalls in the market, such as risks of bacterial contamination and lack of skilled professionals to handle the equipment.

COVID-19 Analysis

The rising prevalence of COVID-19 is projected to moderately impact market growth over the forecast period. The COVID-19 pandemic has unleashed a series of unprecedented events affecting every industry. The pandemic has disrupted several pharmaceutical and R&D sectors in the initial phase. Research activities were kept on hold in the initial phase of the pandemic by many research institutes. According to the published article in ‘Research Professional News in 2020’, a survey showed 65% of the respondents were forced to pause their research because of the pandemic, with a quarter of those yet to restart. Laboratories were closed for months following national lockdowns.

In addition, there has been an important role of chromatography techniques in the diagnosis of COVID-19, which signifies a positive impact on the market growth. An article published in Eclinical Medicine in 2020 talked about a study conducted to understand the feasibility of using breath-analysis to distinguish COVID-19 and other respiratory conditions such as influenza. The study used Gas Chromatography-Ion Mobility Spectrometry (GC-IMS) on these patients and concluded that the development and validation of this approach allowed rapid diagnosis of COVID-19.

Market Drivers

  • Rising demand for ion chromatography in the pharmaceutical industry and drug analysis
    • Ion chromatography is a well-established and popular technique used to quantify and analyze charged species. Ion Chromatography (IC) has developed and matured into an important analytical methodology in various fields, including the pharmaceutical industry. However, reversed-phase chromatography is the most frequently used chromatographic method for analyzing drugs in the pharmaceutical sector. IC serves as an alternative method for ionic species that is often used to confirm the analysis of drugs, including sulfa drugs. The use of ion exchange and ion exclusion chromatography in the pharmaceutical industry is carried out to determine counterions and excipients in “off-the-shelf” drugs.
    • In addition, drugs such as gentamicin, neomycin, bethanechol chloride, and cefadroxil contain Active Pharmaceutical Ingredients (APIs) that can be determined by the IC method in compliance with regulatory standards such as the European Pharmacopoeia and US Pharmacopeia regulations. These regulatory standards and the rising adoption of IC techniques for drug determination are propelling market growth.
  • Growing food safety concerns
  • Increasing R&D funding for chromatographic techniques

Market Restraints

  • Risk of bacterial contamination during ion exchange
    • During ion chromatography, ion exchange resins do not remove microorganisms such as bacteria from the feed water, resulting in bacterial growth. The resin beds accumulate organic matter, which serves as a nutrient source for bacterial growth. This factor can result in limiting the market growth of ion chromatography.
    • The ion exchange resins beds can be treated with disinfectants such as formaldehyde but not with heat or chlorine, as they damage the resin. Furthermore, the lack of skilled personnel to handle the ion chromatography instruments is expected to restrain the market growth during the study period.

Market Opportunities

  • Increasing use of chromatography in the purification of monoclonal antibodies
    • According to the research articles published in Springerlink 2020, ion exchange chromatography is one of the most successful methods for preparing pure monoclonal antibodies (mAbs). An article published in Sciencedirect in 2020 states that the separation of charge variants is a challenge for monoclonal antibodies (mAbs) production. Cation exchange chromatography is being used to serve this purpose, further increasing the demand for procedures such as ion exchange chromatography.
    •  In addition, ion exchange chromatography is also being used to monitor the heterogeneity in mAbs. It is useful because the protein remains in a native state, enabling collected fractions to be tested in a bioactivity assay to establish how a particular modification affects the functional activity of the mAbs.

Value Chain Analysis

  • The global ion chromatography market is growing steadily due to the emerging number of players in the market involved in new product launches, acquisitions, and strategic collaborations. The value chain analysis of the ion chromatography market comprises four major components starting with the R&D and designing, followed by manufacturing the products, distribution & sales, and ends with post-sales services.

Segment Overview

By Technique

  • Based on the techniques of the ion chromatography market, it is divided into ion-exchange chromatography, ion-exclusion chromatography, and ion-pair chromatography
  • Ion-exchange Chromatography
    • The ion-exchange chromatography segment held the major share in 2020. It is a process of separation of ions and polar molecules based on their affinity to ion exchangers. This type of chromatography principle is based on the reversible exchange of ions between the target ions present in the sample solution to the ions present in ion exchangers. Two types of exchangers are used, i.e., cationic and anionic exchangers.
    • The market growth for the ion-exchange chromatography segment can be attributed to the increasing adoption of ion-exchange techniques in the water industry and the food & beverages industry. The technique is also used to check safety, content, and quality in various environmental testing industries. In addition, the technique is also being used to check the presence or amount of ingredients in a sample. Thus, the above-mentioned factors are contributing towards the market growth.
  • Ion-exclusion Chromatography
    • Ion-exclusion chromatography is a process of separation technique used for both analytical scale and simultaneous analysis of ionic species as well as at preparative scale for the separation of strong electrolytes from weak electrolytes and nonelectrolytes. The technique has made the sample analysis less time-consuming and can be run for numerous samples overnight, acting as a fueling factor driving the market growth of this segment.
  • Ion-pair Chromatography
    • Ion Pair Chromatography (IPC) is an effective method for the Reversed-Phase Liquid Chromatographic (RPLC) technique for separating organic ions and partly ionized organic analytes. Increasing demand for IPC and its rising application in industries such as pharmaceuticals is further propelling the market growth.

By Application
Based on application, the ion chromatography market is divided into environmental testing, pharmaceutical industry, food industry, chemical industry, and others.

  • Environmental Testing
    • Ion chromatography has significant advantages in conventional forms of environmental monitoring and testing. The main focus of ion chromatography and its application in environmental analytical chemistry is the qualitative and quantitative analysis of anions and cations. These ions are tested for all types of water for pollution and contaminants. The increasing demand for ion chromatography for environmental testing is fueling the market growth of this segment.
  • Pharmaceutical Industry
    • The pharmaceutical industry was the largest and fastest-growing segment throughout the study period. The availability of government and corporate funding for biotechnology and pharmaceutical research and the rapidly flourishing pharmaceutical industry are a few key driving factors for the segment’s growth.
    • Furthermore, increasing R&D activities in this industry for therapeutic areas, such as HIV/AIDS and cancer, and the increasing focus of pharmaceutical and biotechnology companies on expanding their product pipeline are some of the major factors attributing to the market growth.
  • Food Industry
    • The increasing need for food and drinking water analysis and the development of innovative analytical methods over the past few decades is boosting the market growth of this segment. According to the research article published in 2018 in Science Direct, ion chromatography has good selectivity in food testing, and it can distinguish the composition of many chemical properties in food. Thus, the rising adoption of ion chromatography techniques in the food sector is stimulating this segment’s market growth.
  • Chemical Industry
    • Technological advancements in the chemical industry and the rising need to distinguish between chemical forms of elements are factors contributing to the growth of this segment.
  • Others
    • The other ion chromatography applications include drug development, forensics, nutraceutical industry, wastewater analysis, etc. The increasing demand for ion chromatography in these applications is boosting the market growth of this segment.

By Region

  • North America:
    • The ion chromatography market in North America accounted for the largest share in 2020. This growth is attributed to the presence of constant technological developments followed by discoveries triggering the adoption of novel ion separation methods by the major players of this region. These players are involved in new product launches, acquisitions, expansions, and strategic collaborations. For instance, in March 2020, Danaher Corporation (US) acquired the biopharma business of General Electric Life Sciences (US), now called Cytiva, for USD 21.4 billion. This move has boosted the company’s position in the life sciences industry.
  • Europe:
    • The European ion chromatography market is driven by developed healthcare infrastructure, increasing R&D spendings, and adopting High-Performance Liquid Chromatography (HPLC) for food analysis in the food & beverage industry and the pharmaceutical industry for factory testing and quality control, enhancing the popularity of LC-MS (Liquid Chromatography-Mass Spectrography).
  • Asia-Pacific:
    • The Asia-Pacific ion chromatography market is projected to witness growth at the highest CAGR during the forecast period. This is due to factors such as the improving healthcare infrastructure, rising demand for ion chromatography in industries such as environmental testing, pharmaceutical industries, forensics, and the improvement in techniques making the utilization of chromatography processes more feasible and accessible.
    • In addition, factors such as the rising R&D expenditure in the Asia-Pacific region are another driving factor for the Asia-Pacific ion chromatography market. For instance, according to data by Chinapower Organization in 2018, China’s nominal spending on R&D is rapidly growing and witnessed a more than 35-fold increase from 1991 to 2018 from USD 13.1 billion to USD 462.6 billion. Moreover, countries such as China are also expanding their R&D facilities. For instance, China has 522 important laboratories and 350 engineering research institutes operational by the end of 2020, working on approximately 457,000 projects. Similarly, in January 2018, Danaher (US) invested USD 100 million over three years to expand in India, primarily through acquisitions.
  • Rest of the World:
    • The ion chromatography market in the Rest of the World is driven by technological development in manufacturing, screening technologies, the biotechnology industry, and assays. The increasing number of government initiatives for improving the healthcare sector is another factor boosting the growth of the market in this region.

Competitive Landscape

  • The ion chromatography market is profitable, both for existing players as well as new entrants. A substantial level of competitive rivalry is witnessed among the market players. Based on the analysis, market players have adopted different strategies and innovative R&D techniques to expand their business and secure their position in the global ion chromatography market. The prominent players are involved in new product launches & developments, strategic agreements, and joint ventures to mark their presence in the market. In addition, the presence of regulatory standards such as the United States Environmental Protection Agency (USEPA) and the American Society for Testing and Materials (ASTM) is also a stimulating factor for market growth.
  • The major market players are Thermo Fisher Scientific (US), Metrohm (Switzerland), Tosoh Bioscience (Japan), Shimadzu (Japan), Qingdao Shenghan Chromatograph Technology Co., Ltd (China), MembraPure GmbH (Germany), Nittoseiko Analytech Co., Ltd (Japan), Qingdao Puren Instrument (China), East & West Analytical Instruments (China), Qingdao Luhai (China), Sykam (Germany), and Cecil Instruments (UK).
  • Thermo Fisher Scientific (US) has a robust industry experience and is one of the leading companies in the ion chromatography market. Furthermore, a high customer satisfaction level, exceptional performance in new markets, and a strong product portfolio add to the company’s competitive advantage.

Key Players

  • Thermo Fisher Scientific (US)
  • Metrohm (Switzerland)
  • Tosoh Bioscience (Japan)
  • Shimadzu (Japan)
  • Qingdao Shenghan Chromatograph Technology Co., Ltd (China)
  • MembraPure GmbH (Germany)
  • Nittoseiko Analytech Co., Ltd (Japan)
  • Qingdao Puren Instrument (China)
  • East & West Analytical Instruments (China)
  • Qingdao Luhai (China)
  • Sykam (Germany)
  • Cecil Instruments (UK)

Recent Developments

  • In September 2021, Thermo Fisher Scientific (US) introduced a new Mass Spectrometry (MS) portfolio to advance quantitative analysis. The company’s integration with liquid-and ion-chromatography systems and software deliver robust quantitative application solutions.
  • In January 2021, Novasep (France), a leading supplier of services and technologies for the life sciences industry, and Sartorius Stedim Biotech (Germany), a subgroup of the life science company Sartorius, entered into a collaborative agreement regarding the proposed sale of Novasep’s chromatography equipment division.

Report Overview:

  • The study covers the existing short-term and long-term market effects, as well as helping decision-makers to draught short-term and long-term plans for businesses by region. The report covers major regions in North America, Europe, Asia-Pacific, and the Rest of the World. The report analyzes market drivers, restraints, opportunities, challenges, Porter’s Five Forces, value chain, and impact of COVID-19 on the market.

Scope of the Report

  • The scope of the global ion chromatography market study includes a market size analysis and a detailed analysis of the manufacturer’s products and strategies. The market has been segmented based on product, application, end user, and region.

Study Objectives

  • To provide a detailed analysis of the market structure and forecast for the next seven years of the various segments and sub-segments of the ion chromatography market.
  • To provide insights about factors affecting the market growth.
  • To analyze the ion chromatography market based on various factors— price analysis, supply chain analysis, Porter’s five force analysis, etc.
  • To provide historical and forecast revenue of the market segments and sub-segments with respect to four main regions and their countries- North America, Europe, Asia-Pacific, and the Rest of the World.
  • To provide country-level analysis of the market with respect to the current market size and future prospective.
  • To provide country-level analysis of the market for segments by technique and application.
  • To provide strategic profiling of key players in the market, comprehensively analyze their core competencies, and draw a competitive market landscape.

To track and analyze competitive developments such as joint ventures, strategic alliances, mergers & acquisitions, new product developments, and R&D in the ion chromatography market.

Market Segmentation

Global Ion Chromatography Market, by Technique

  • Ion-exchange Chromatography
  • Ion-exclusion Chromatography
  • Ion-pair Chromatography

Global Ion chromatography Market, by Application  

  • Environmental Testing
  • Pharmaceutical Industry
  • Food Industry
  • Chemical Industry
  • Others

Global Ion Chromatography Market, by Region

  • North America
    • US
    • Canada
  • Europe
    • Germany
    • France
    • UK
    • Italy
    • Spain
    • Rest of Europe
  • Asia-Pacific
    • China
    • Japan
    • India
    • Australia
    • South Korea
    • Rest of Asia-Pacific
  • Rest of the World
    • Middle East
    • Africa
    • Latin America

 

Report Scope:
Report Attribute/MetricDetails
  Market Size  2027: ~USD 3,794.96 Million
  CAGR  ~8.51%
  Base Year  2021
  Forecast Period  2022–2030
  Historical Data  2018 & 2019
  Forecast Units  Value (USD Million)
  Report Coverage  Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
  Segments Covered  Product and Application
  Geographies Covered  North America, Europe, Asia-Pacific, Rest of the World
  Key Vendors  • Thermo Fisher Scientific (US) • Metrohm (Switzerland) • Tosoh Bioscience (Japan) • Shimadzu (Japan) • Qingdao Shenghan Chromatograph Technology Co., Ltd (China) • MembraPure GmbH (Germany) • Nittoseiko Analytech Co., Ltd (Japan) • Qingdao Puren Instrument (China) • East & West Analytical Instruments (China) • Qingdao Luhai (China) • Sykam (Germany) • Cecil Instruments (UK)
  Key Market Opportunities  • Increasing use of chromatography in the purification of monoclonal antibodies.
  Key Market Drivers  • Rising demand for ion chromatography in the pharmaceutical industry and drug analysis • Growing food safety concerns

 

Table of Contents

1. REPORT PROLOGUE

2. MARKET INTRODUCTION

2.1. Definition

2.2. Scope Of The Study

2.2.1. Research Objective

2.2.2. Assumptions

2.2.3. Limitations

3. RESEARCH METHODOLOGY

3.1. Overview

3.2. Data Mining

3.3. Secondary Research

3.4. Primary Research

3.4.1. Primary Interviews And Information Gathering Process

3.4.2. Breakdown Of Primary Respondents

3.5. Forecasting Techniques

3.6. Market Size Estimation

3.6.1. Bottom-Up Approach

3.6.2. Top-Down Approach

3.7. Data Triangulation

3.8. Validation

4. MARKET DYNAMICS

4.1. Overview

4.2. Drivers

4.3. Restraints

4.4. Opportunities

5. MARKET FACTOR ANALYSIS

5.1. Porter’s Five Forces Analysis

5.1.1. Bargaining Power Of Suppliers

5.1.2. Bargaining Power Of Buyers

5.1.3. Threat Of New Entrants

5.1.4. Threat Of Substitutes

5.1.5. Intensity Of Rivalry

5.2. Value Chain Analysis

5.3. COVID-19 Impact Analysis

5.3.1. Market Impact Analysis

5.3.2. Impact On Supply Chain

5.3.3. Regional Impact

5.3.4. Opportunity And Threat Analysis

6. GLOBAL ION CHROMATOGRAPHY MARKET, BY TECHNIQUE

6.1. Overview

6.2. Ion-Exchange Chromatography

Market Estimates & Forecast, By Region, 2018–2027

Market Estimates & Forecast, By Country, 2018–2027

6.3. Ion-Exclusion Chromatography

Market Estimates & Forecast, By Region, 2018–2027

Market Estimates & Forecast, By Country, 2018–2027

6.4. Ion-Pair Chromatography

Market Estimates & Forecast, By Region, 2018–2027

Market Estimates & Forecast, By Country, 2018–2027

7. GLOBAL ION CHROMATOGRAPHY MARKET, BY APPLICATION

7.1. Overview

7.2. Environmental Testing

Market Estimates & Forecast, By Region, 2018–2027

Market Estimates & Forecast, By Country, 2018–2027

7.3. Pharmaceutical Industry

Market Estimates & Forecast, By Region, 2018–2027

Market Estimates & Forecast, By Country, 2018–2027

7.4. Food Industry

Market Estimates & Forecast, By Region, 2018–2027

Market Estimates & Forecast, By Country, 2018–2027

7.5. Chemical Industry

Market Estimates & Forecast, By Region, 2018–2027

Market Estimates & Forecast, By Country, 2018–2027

7.6. Others

Market Estimates & Forecast, By Region, 2018–2027

Market Estimates & Forecast, By Country, 2018–2027

8. GLOBAL ION CHROMATOGRAPHY MARKET, BY REGION

8.1. Overview

8.2. North America

8.2.1. US

8.2.2. Canada

8.3. Europe

8.3.1. Germany

8.3.2. France

8.3.3. Italy

8.3.4. Spain

8.3.5. UK

8.3.6. Rest Of Europe

8.4. Asia-Pacific

8.4.1. Japan

8.4.2. China

8.4.3. India

8.4.4. Australia

8.4.5. South Korea

8.4.6. Rest Of Asia-Pacific

8.5. Rest Of The World

8.5.1. Middle East

8.5.2. Africa

8.5.3. Latin America

9. COMPANY LANDSCAPE

9.1. Overview

9.2. Competitive Analysis

9.3. Market Share Analysis

9.4. Major Growth Strategy In The Global Ion Chromatography Market

9.5. Competitive Benchmarking

9.6. Leading Players In Terms Of Number Of Developments In The Global Ion Chromatography Market

9.7. Key Developments And Growth Strategies

9.7.1. New Product Launch/Service Deployment

9.7.2. Merger & Acquisitions

9.7.3. Joint Ventures

9.8. Major Players Financial Matrix

9.8.1. Sales & Operating Income, 2020

9.8.2. Major Players R&D Expenditure, 2020

10. COMPANY PROFILES

10.1. ThermoFisher Scientific

10.1.1. Company Overview

10.1.2. Products Offered

10.1.3. Financial Overview

10.1.4. Key Developments

10.1.5. SWOT Analysis

10.1.6. Key Strategies

10.2. Metrohm

10.2.1. Company Overview

10.2.2. Products Offered

10.2.3. Financial Overview

10.2.4. Key Developments

10.2.5. SWOT Analysis

10.2.6. Key Strategies

10.3. Qingdao Shenghan

10.3.1. Company Overview

10.3.2. Products Offered

10.3.3. Financial Overview

10.3.4. Key Developments

10.3.5. SWOT Analysis

10.3.6. Key Strategies

10.4. Tosoh Bioscience

10.4.1. Company Overview

10.4.2. Products Offered

10.4.3. Financial Overview

10.4.4. Key Developments

10.4.5. SWOT Analysis

10.4.6. Key Strategies

10.5. Shimadzu

10.5.1. Company Overview

10.5.2. Products Offered

10.5.3. Financial Overview

10.5.4. Key Developments

10.5.5. SWOT Analysis

10.5.6. Key Strategies

10.6. MembraPure GmbH

10.6.1. Company Overview

10.6.2. Products Offered

10.6.3. Financial Overview

10.6.4. Key Developments

10.6.5. SWOT Analysis

10.6.6. Key Strategies

10.7. Nittoseiko Analytech Co., Ltd

10.7.1. Company Overview

10.7.2. Products Offered

10.7.3. Financial Overview

10.7.4. Key Developments

10.7.5. SWOT Analysis

10.7.6. Key Strategies

10.8. Qingdao Puren Instrument

10.8.1. Company Overview

10.8.2. Products Offered

10.8.3. Financial Overview

10.8.4. Key Developments

10.8.5. SWOT Analysis

10.8.6. Key Strategies

10.9. East & West Analytical Instruments

10.9.1. Company Overview

10.9.2. Products Offered

10.9.3. Financial Overview

10.9.4. Key Developments

10.9.5. SWOT Analysis

10.9.6. Key Strategies

10.10. Qingdao Luhai

10.10.1. Company Overview

10.10.2. Products Offered

10.10.3. Financial Overview

10.10.4. Key Developments

10.10.5. SWOT Analysis

10.10.6. Key Strategies

10.11. Sykam

10.11.1. Company Overview

10.11.2. Products Offered

10.11.3. Financial Overview

10.11.4. Key Developments

10.11.5. SWOT Analysis

10.11.6. Key Strategies

10.12. Cecil Instruments

10.12.1. Company Overview

10.12.2. Products Offered

10.12.3. Financial Overview

10.12.4. Key Developments

10.12.5. SWOT Analysis

10.12.6. Key Strategies

10.13. Others

Major Companies

  • Thermo Fisher Scientific (US)
  • Metrohm (Switzerland)
  • Tosoh Bioscience (Japan)
  • Shimadzu (Japan)
  • Qingdao Shenghan Chromatograph Technology Co., Ltd (China)
  • MembraPure GmbH (Germany)
  • Nittoseiko Analytech Co., Ltd (Japan)
  • Qingdao Puren Instrument (China)
  • East & West Analytical Instruments (China)
  • Qingdao Luhai (China)
  • Sykam (Germany)
  • Cecil Instruments (UK)

Segmentation

Global Ion Chromatography Market, by Technique

  • Ion-exchange Chromatography
  • Ion-exclusion Chromatography
  • Ion-pair Chromatography

Global Ion chromatography Market, by Application  

  • Environmental Testing
  • Pharmaceutical Industry
  • Food Industry
  • Chemical Industry
  • Others

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