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Custom Nucleic Acid Market Analysis- Industry Size, Share, Research Report, Insights, Covid-19 Impact, Statistics, Trends, Growth and Forecast 2024-2032

Published Date: April, 2024
Base Year: 2023
Delivery Format: PDF+ Excel
Historical Year: 2017-2023
No of Pages: 227
Forecast Year: 2024-2032

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Market Overview:

The custom nucleic acid market is a key player in the biotechnology and life sciences sectors, offering tailored solutions for diverse applications, including research, diagnostics, and therapeutics. Custom nucleic acids, such as oligonucleotides and synthetic DNA/RNA fragments, serve as fundamental tools for genetic analysis and manipulation. As advancements in genomics and personalized medicine continue, the custom nucleic acid market experiences sustained growth and evolution.


Custom nucleic acids refer to synthetic DNA or RNA sequences designed and produced according to specific customer requirements. These sequences find applications in various fields, including molecular biology, genomics, diagnostics, and drug development, providing researchers and scientists with precise tools for genetic analysis and manipulation.

Executive Summary:

The custom nucleic acid market is witnessing robust growth, fueled by advancements in genomics, increasing demand for personalized medicine, and expanding applications in molecular diagnostics. While the market offers lucrative opportunities, challenges related to quality control, standardization, and regulatory compliance require attention. A comprehensive understanding of key market insights, technological trends, and emerging applications is essential for stakeholders aiming to capitalize on the evolving landscape.

Custom Nucleic Acid Market

Key Market Insights:

  1. Rapid Advancements in Genomic Technologies: Ongoing advancements in genomic technologies, including next-generation sequencing (NGS) and gene editing tools like CRISPR-Cas9, drive the demand for custom nucleic acids in diverse research applications.
  2. Growing Emphasis on Personalized Medicine: The shift towards personalized medicine, with a focus on individualized treatment plans based on genetic information, fuels the demand for custom nucleic acids in diagnostic and therapeutic applications.
  3. Expanding Applications in Drug Development: The use of custom nucleic acids in drug development, particularly in the synthesis of antisense oligonucleotides and RNA therapeutics, contributes to the market’s growth.
  4. Quality Control and Standardization Challenges: Ensuring the quality and consistency of custom nucleic acids poses challenges, necessitating stringent quality control measures and standardization across manufacturing processes.

Market Drivers:

  1. Genomic Research and Precision Medicine: Increasing investments in genomic research and the rise of precision medicine initiatives propel the demand for custom nucleic acids, serving as essential tools for genetic analysis and diagnostics.
  2. Expanding Applications in Therapeutics: The exploration of nucleic acid-based therapeutics, including RNA interference (RNAi) and gene therapy, drives the demand for custom-designed sequences tailored for specific therapeutic purposes.
  3. Rising Demand for Synthetic Biology: The expanding field of synthetic biology relies heavily on custom nucleic acids for the construction of engineered biological systems and the synthesis of artificial genes.
  4. Technological Innovations in Nucleic Acid Synthesis: Ongoing innovations in nucleic acid synthesis technologies, such as phosphoramidite chemistry and solid-phase synthesis, contribute to the market’s growth.

Market Restraints:

  1. Regulatory Challenges in Quality Assurance: Meeting regulatory requirements for quality assurance and standardization poses challenges for market players, necessitating adherence to evolving guidelines and standards.
  2. High Cost of Custom Synthesis: The high cost associated with custom nucleic acid synthesis limits widespread adoption, especially in academic and smaller research institutions with budget constraints.

Market Opportunities:

  1. Expansion of Diagnostic Applications: The expanding applications of custom nucleic acids in diagnostics, including molecular diagnostics and companion diagnostics, present significant growth opportunities.
  2. Technological Integration with Automation: Integrating nucleic acid synthesis processes with automation technologies enhances efficiency, reduces costs, and opens avenues for scaling up production.
  3. Collaborations for Research and Development: Collaborative efforts between custom nucleic acid manufacturers and research institutions create opportunities for advancing technologies, ensuring quality, and exploring novel applications. The custom nucleic acid market operates in a dynamic landscape influenced by factors such as technological advancements, regulatory changes, and the evolving needs of the biotechnology and pharmaceutical industries. Continuous adaptation to these dynamics is essential for stakeholders to stay competitive and capitalize on emerging opportunities.

Regional Analysis:

  1. North America: The North American custom nucleic acid market is characterized by a strong presence of biotechnology and pharmaceutical companies, research institutions, and a supportive regulatory environment. The region’s focus on genomics research and personalized medicine drives market growth.
  2. Europe: Europe’s market benefits from a robust biotechnology sector and increasing investments in life sciences research. Collaborations between academic institutions and industry players contribute to advancements in custom nucleic acid technologies.
  3. Asia Pacific: The Asia Pacific region presents lucrative opportunities for market growth, driven by the growing biotechnology and pharmaceutical sectors, increased research funding, and a rising emphasis on genomics in countries like China and Japan.
  4. Latin America: Latin America experiences a gradual expansion of the custom nucleic acid market, with an increasing focus on research and development activities in genetics and molecular biology.
  5. Middle East and Africa: The market in this region is characterized by emerging opportunities in genomics research and diagnostic applications, with a growing awareness of personalized medicine.

Competitive Landscape:

The custom nucleic acid market features a competitive landscape with key players driving innovation and market expansion. Notable companies include:

  1. Integrated DNA Technologies, Inc.
  2. Eurofins Scientific SE
  3. Thermo Fisher Scientific Inc.
  4. GenScript Biotech Corporation
  5. Bio-Synthesis Inc.
  6. Twist Bioscience Corporation
  7. ATDBio Ltd.
  8. Merck KGaA (Sigma-Aldrich)
  9. Kaneka Eurogentec S.A.
  10. LGC Biosearch Technologies

Strategies employed by these players include product launches, collaborations, acquisitions, and investments in research and development.


The custom nucleic acid market can be segmented based on various factors, including type of nucleic acid (DNA or RNA), application (research, diagnostics, therapeutics), and end-user (academic and research institutions, pharmaceutical companies, diagnostic laboratories).

Category-wise Insights:

  1. Oligonucleotides: Custom-designed oligonucleotides find applications in various research and diagnostic fields, including PCR, DNA sequencing, and gene editing technologies.
  2. Synthetic DNA/RNA Fragments: The synthesis of custom DNA and RNA fragments plays a crucial role in therapeutic applications, including RNA therapeutics and gene synthesis.

Key Benefits for Industry Participants and Stakeholders:

  1. Tailored Solutions for Research: Custom nucleic acids offer researchers precise tools for genetic analysis, enabling tailored solutions for diverse research applications.
  2. Advancements in Diagnostics: The use of custom nucleic acids in molecular diagnostics enhances the accuracy and specificity of diagnostic tests, contributing to improved disease detection.
  3. Innovation in Therapeutics: Custom-designed nucleic acids play a pivotal role in advancing nucleic acid-based therapeutics, fostering innovation in areas such as gene therapy and RNA interference.
  4. Collaboration Opportunities: Collaborations between custom nucleic acid manufacturers, research institutions, and pharmaceutical companies create opportunities for knowledge exchange and advancements in technology.

SWOT Analysis:


  • Advancements in nucleic acid synthesis technologies
  • Growing applications in diagnostics and therapeutics
  • Strong presence of key market players
  • Increasing focus on personalized medicine


  • Regulatory challenges and quality control complexities
  • High costs associated with custom nucleic acid synthesis
  • Limited adoption in resource-constrained settings
  • Potential for supply chain disruptions


  • Expansion of diagnostic applications
  • Integration with automation technologies
  • Collaborations for research and development
  • Emerging markets and untapped regions


  • Evolving regulatory landscape impacting compliance
  • Intense competition among market players
  • Economic uncertainties affecting research funding
  • Rapid changes in technology requiring continuous adaptation

Market Key Trends:

  1. Advancements in Gene Editing Technologies: The continuous evolution of gene editing tools, such as CRISPR-Cas9, drives the demand for custom nucleic acids tailored for precise genetic modifications.
  2. Emergence of RNA Therapeutics: The rise of RNA therapeutics, including mRNA vaccines, emphasizes the importance of custom RNA fragments in drug development and therapeutic applications.

Covid-19 Impact:

The COVID-19 pandemic has influenced the custom nucleic acid market, with increased demand for synthetic DNA/RNA fragments for diagnostic purposes, including the development of molecular tests and vaccines. The pandemic underscored the importance of rapid and precise nucleic acid synthesis in responding to emerging infectious diseases.

Key Industry Developments:

  1. Expansion of NGS Applications: Next-generation sequencing applications continue to expand, driving the demand for custom nucleic acids in genomics research and diagnostics.
  2. Focus on CRISPR-Cas9 Applications: The exploration of CRISPR-Cas9 for gene editing applications fuels the demand for custom-designed nucleic acids for precise and targeted modifications.

Analyst Suggestions:

  1. Quality Control Measures: Stakeholders should prioritize robust quality control measures to ensure the consistency and reliability of custom nucleic acid products.
  2. Strategic Collaborations: Forming strategic collaborations with research institutions and diagnostic laboratories can foster innovation and address challenges related to standardization and regulatory compliance.
  3. Education and Training Initiatives: Initiatives aimed at educating researchers and healthcare professionals about the applications and benefits of custom nucleic acids can enhance market acceptance and adoption.

Future Outlook:

The custom nucleic acid market is poised for sustained growth, driven by advancements in genomic technologies, expanding applications in diagnostics and therapeutics, and the increasing focus on personalized medicine. Continuous innovation, strategic collaborations, and efforts to address regulatory challenges will shape the future trajectory of the market.


In conclusion, the custom nucleic acid market stands at the forefront of molecular biology and genetic research, offering tailored solutions for diverse applications. As genomics research advances, and personalized medicine gains prominence, the market plays a pivotal role in providing researchers and healthcare professionals with precise tools for genetic analysis and manipulation. While challenges related to quality control and regulatory compliance persist, ongoing innovations, strategic collaborations, and education initiatives position the custom nucleic acid market as a key player in shaping the future of genomics, diagnostics, and therapeutics.

Custom Nucleic Acid Market.

Segmentation Details
Type Oligonucleotides, DNA Probes, RNA Probes, Others
Application PCR, Sequencing, Microarray, Others
End User Research Institutes, Biotechnology Companies, Academic Institutions, Others
Region North America, Europe, Asia-Pacific, Latin America, Middle East and Africa

Leading Companies in the Custom Nucleic Acid Market:

  1. Thermo Fisher Scientific Inc.
  2. Integrated DNA Technologies, Inc. (IDT)
  3. Eurofins Genomics
  4. GenScript Biotech Corporation
  5. ATDBio Ltd.
  6. Twist Bioscience Corporation
  7. LGC Biosearch Technologies
  8. Gene Link
  9. Bio-Synthesis, Inc.
  10. Biomatik Corporation

North America
o US
o Canada
o Mexico

o Germany
o Italy
o France
o UK
o Spain
o Denmark
o Sweden
o Austria
o Belgium
o Finland
o Turkey
o Poland
o Russia
o Greece
o Switzerland
o Netherlands
o Norway
o Portugal
o Rest of Europe

Asia Pacific
o China
o Japan
o India
o South Korea
o Indonesia
o Malaysia
o Kazakhstan
o Taiwan
o Vietnam
o Thailand
o Philippines
o Singapore
o Australia
o New Zealand
o Rest of Asia Pacific

South America
o Brazil
o Argentina
o Colombia
o Chile
o Peru
o Rest of South America

The Middle East & Africa
o Saudi Arabia
o Qatar
o South Africa
o Israel
o Kuwait
o Oman
o North Africa
o West Africa
o Rest of MEA

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