The global mixed-mode chromatography resin market size was valued at USD XXX million in 2021 and is anticipated to reach USD 388 Mn by 2030 at an impressive CAGR of 15.7% during the forecast period covering 2022 to 2030 , coupled with rising use of mixed-mode resin for therapeutic drug treatment. The rise in the number of contract manufacturing organizations (CMOs) and contract research organizations (CROs) is also expected to drive the market from 2022 to 2030.
Demand in the market has been on a rise thanks to ongoing developments in drug discovery processes by leading pharmaceutical companies, particularly to find a cure for widespread diseases such as Ebola, Zika, and H1N1. Big and established pharma and biopharma companies now outsource most biopharmaceutical drug discovery and development activities.
Chromatography helps companies develop and manufacture biological pharmaceutical tools to achieve safety and quality. Currently, chromatography is applied like a valued technique for purification, separation, and analysis of compounds present in complex mixtures and used in pharmaceutical, chemical, biochemistry, and environmental science.
The high cost of raw material, coupled with the need for a highly-skilled workforce to perform these techniques has resulted in increasing the overall cost of chromatography. This high cost compared to other separation techniques is expected to act as a restraint for the market over the forecast period.
Mixed-Mode Chromatography Resin Market Report Scope and Segmentation | |
|---|---|
| ATTRIBUTES | DETAILS |
| ESTIMATED YEAR | 2022 |
| BASE YEAR | 2021 |
| FORECAST YEAR | 2030 |
| HISTORICAL YEAR | 2017-2021 |
| UNIT | Value (USD Million/Billion) |
| BY REGION | North America, Europe, Asia Pacific, Latin America, Middle East and Africa |
Mixed Mode Chromatography Resin Market Trends
Biosimilars are the world’s fastest-growing biologics market. Due to the expiration of patents in the market, many companies are encouraged to participate in biosimilars. One of the most important bio-separation techniques utilized in the production of biosimilar antibodies is chromatography. During the forecast period, rising demand for generic medicines is expected to increase the use of chromatographic resins. Other chronic diseases for which biosimilars are developed include meningitis, cancer, adult T-cell leukemia, obesity, hypertension, and influenza E. This factor is expected to drive market growth during the forecast period.
The COVID-19 pandemic has affected several industries and businesses experiencing losses as lockdowns were imposed and supply lines were interrupted. The market, on the other hand, had seen a rise in demand as a result of the pandemic. This is because one of the key applications of these resins is the generation of antibodies. This is being used by medicinal companies to create medicines that fight and lessen the severity of COVID-19 as well as other disorders in general.
The cost of raw materials has increased in parallel with the need for highly specialized workers, increasing the overall cost of chromatography. The higher cost compared to other separation processes is expected to hamper the market over the forecast period.
The key driver for the market is the increase in the number of manufacturing and research companies. The rise of drug discovery procedures by major pharmaceutical companies for diseases like Zika, Ebola, and H1N1 is also propelling the market forward. The development of biopharmaceutical drugs as a result of advances in pharmaceutical and biopharma is another opportunity for the market to flourish.
End-use Insights
The use of chromatography in the pharmaceutical sector as per the U.S. FDA regulations is witnessing growth, which is favorably influencing the market. The European Medical Agency’s (EMA) initiative to ensure drug safety is likely to trigger the growth of the global market.
Increasing demand for therapeutic antibodies for the treatment of patients is also a major driver that is triggering industry growth. The trend of replacing conventional separation techniques such as filtration and distillation with chromatography has also driven innovation for the application of chromatography in various new segments.
Regional Insights
North America is expected to remain a key region in the global market, driven primarily by the U.S. The country has been enjoying robust growth due to strong government spending in research and development activities.
Demand in the Asia Pacific is expected to grow at an exponential rate. This development can be credited to many initiatives by Chinese and Indian governments to boost their biotechnology and pharmaceutical sectors. The Asia Pacific is anticipated to continue as the fastest-growing regional market during the forecast period.
High healthcare expenditure, increasing disposable in emerging economies, and high availability of cheap and skilled workforce is expected to boost the biotechnology sector in emerging economies of Asia Pacific, which will in turn propel the overall market.
Mixed Mode Chromatography Resin Market Share Insights
GE Healthcare Lifesciences, Merck KGaA, Tosoh Corp, Purolite Corp, Danaher Corp, and Bio-Rad Labs are some of the major market players. In November 2015, Sigma-Aldrich was acquired by Merck KGaA and this allowed Merck to foray into the chromatography market. Extensive R&D in the global resin industry has driven the development of novel resin products that have better productivity compared to conventional resins.
Recent Developments
- In June 2022, Tosoh Bioscience GmbH, a supplier of chromatographic solutions, announced the introduction of SkillPak 50 and 200 pre-packed columns. These columns are used for the development of antibody fragments, viruses, ADCs, monoclonal antibodies, and oligonucleotides
- In March 2021, Bio-Rad Laboratories, Inc., a global leader in clinical diagnostic products and life science research, announced its partnership with Roche, a diagnostic company. This partnership aims to provide its customers with complete access to the products of InteliQ
- In April 2020, Bio-Rad Laboratories, Inc., a global leader in clinical diagnostic products and life science research, acquired Celsee, Inc., a supplier of instruments for isolation, analysis, and detection of single cells. This acquisition will help to extend the reach of innovative products and technologies in the growing world
Mixed Mode Chromatography Resin Market Report Scope
Global Mixed Mode Chromatography Resin Market Segmentation
| By Type |
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| By Application |
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Key Market Players
- Bio-Rad Laboratories
- Bio-Works Company Ltd.
- Danaher Corporation
- GE Healthcare Life Sciences
- Merck
- Pall Corporation
- Purolite Corporation
- Sepragen Corporation
- Thermo Fisher Scientific
- Tosoh Corporation
- JSR Micro Inc.
- Kaneka Corporation
- Knauer Gmbh
- Life Technology Corporation
- Others
Regional Outlook
- North America
- US
- Canada
- Mexico
- Europe
- Germany
- Italy
- France
- UK
- Spain
- Poland
- Russia
- The Netherlands
- Norway
- Czech Republic
- Rest of Europe
- Asia Pacific
- China
- Japan
- India
- South Korea
- Indonesia
- Malaysia
- Thailand
- Singapore
- Australia & New Zealand
- Rest of Asia Pacific
- South America
- Brazil
- Argentina
- Colombia
- Rest of South America
- The Middle East & Africa
- Saudi Arabia
- UAE
- South Africa
- Northern Africa
- Rest of MEA