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Mixed-Mode Chromatography Resin Market Analysis- Industry Size, Share, Research Report, Insights, Covid-19 Impact, Statistics, Trends, Growth and Forecast 2022-2030

Published Date: July, 2022
No of Pages: 153
Delivery Format: PDF + Excel

$2,950.00

The global mixed-mode chromatography resin market size was valued at USD XXX million in 2021 and is anticipated to reach USD 388 Mn by 2030 at an impressive CAGR of 15.7% during the forecast period covering 2022 to 2030 , coupled with rising use of mixed-mode resin for therapeutic drug treatment. The rise in the number of contract manufacturing organizations (CMOs) and contract research organizations (CROs) is also expected to drive the market from 2022 to 2030.

Demand in the market has been on a rise thanks to ongoing developments in drug discovery processes by leading pharmaceutical companies, particularly to find a cure for widespread diseases such as Ebola, Zika, and H1N1. Big and established pharma and biopharma companies now outsource most biopharmaceutical drug discovery and development activities.

Chromatography helps companies develop and manufacture biological pharmaceutical tools to achieve safety and quality. Currently, chromatography is applied like a valued technique for purification, separation, and analysis of compounds present in complex mixtures and used in pharmaceutical, chemical, biochemistry, and environmental science.

The high cost of raw material, coupled with the need for a highly-skilled workforce to perform these techniques has resulted in increasing the overall cost of chromatography. This high cost compared to other separation techniques is expected to act as a restraint for the market over the forecast period.

Mixed-Mode Chromatography Resin Market Report Scope and Segmentation

ATTRIBUTESDETAILS
ESTIMATED YEAR2022
BASE YEAR2021
FORECAST YEAR2030
HISTORICAL YEAR2017-2021
UNITValue (USD Million/Billion)
BY REGIONNorth America, Europe, Asia Pacific, Latin America, Middle East and Africa

Mixed Mode Chromatography Resin Market Trends

Biosimilars are the world’s fastest-growing biologics market. Due to the expiration of patents in the market, many companies are encouraged to participate in biosimilars. One of the most important bio-separation techniques utilized in the production of biosimilar antibodies is chromatography. During the forecast period, rising demand for generic medicines is expected to increase the use of chromatographic resins. Other chronic diseases for which biosimilars are developed include meningitis, cancer, adult T-cell leukemia, obesity, hypertension, and influenza E. This factor is expected to drive market growth during the forecast period.

The COVID-19 pandemic has affected several industries and businesses experiencing losses as lockdowns were imposed and supply lines were interrupted. The market, on the other hand, had seen a rise in demand as a result of the pandemic. This is because one of the key applications of these resins is the generation of antibodies. This is being used by medicinal companies to create medicines that fight and lessen the severity of COVID-19 as well as other disorders in general.

The cost of raw materials has increased in parallel with the need for highly specialized workers, increasing the overall cost of chromatography. The higher cost compared to other separation processes is expected to hamper the market over the forecast period.

The key driver for the market is the increase in the number of manufacturing and research companies. The rise of drug discovery procedures by major pharmaceutical companies for diseases like Zika, Ebola, and H1N1 is also propelling the market forward. The development of biopharmaceutical drugs as a result of advances in pharmaceutical and biopharma is another opportunity for the market to flourish.

End-use Insights

The use of chromatography in the pharmaceutical sector as per the U.S. FDA regulations is witnessing growth, which is favorably influencing the market. The European Medical Agency’s (EMA) initiative to ensure drug safety is likely to trigger the growth of the global market.

Increasing demand for therapeutic antibodies for the treatment of patients is also a major driver that is triggering industry growth. The trend of replacing conventional separation techniques such as filtration and distillation with chromatography has also driven innovation for the application of chromatography in various new segments.

Regional Insights

North America is expected to remain a key region in the global market, driven primarily by the U.S. The country has been enjoying robust growth due to strong government spending in research and development activities.

Demand in the Asia Pacific is expected to grow at an exponential rate. This development can be credited to many initiatives by Chinese and Indian governments to boost their biotechnology and pharmaceutical sectors. The Asia Pacific is anticipated to continue as the fastest-growing regional market during the forecast period.

High healthcare expenditure, increasing disposable in emerging economies, and high availability of cheap and skilled workforce is expected to boost the biotechnology sector in emerging economies of Asia Pacific, which will in turn propel the overall market.

Mixed Mode Chromatography Resin Market Share Insights

GE Healthcare Lifesciences, Merck KGaA, Tosoh Corp, Purolite Corp, Danaher Corp, and Bio-Rad Labs are some of the major market players. In November 2015, Sigma-Aldrich was acquired by Merck KGaA and this allowed Merck to foray into the chromatography market. Extensive R&D in the global resin industry has driven the development of novel resin products that have better productivity compared to conventional resins.

Recent Developments

  • In June 2022, Tosoh Bioscience GmbH, a supplier of chromatographic solutions, announced the introduction of SkillPak 50 and 200 pre-packed columns. These columns are used for the development of antibody fragments, viruses, ADCs, monoclonal antibodies, and oligonucleotides
  • In March 2021, Bio-Rad Laboratories, Inc., a global leader in clinical diagnostic products and life science research, announced its partnership with Roche, a diagnostic company. This partnership aims to provide its customers with complete access to the products of InteliQ
  • In April 2020, Bio-Rad Laboratories, Inc., a global leader in clinical diagnostic products and life science research, acquired Celsee, Inc., a supplier of instruments for isolation, analysis, and detection of single cells. This acquisition will help to extend the reach of innovative products and technologies in the growing world

Mixed Mode Chromatography Resin Market Report Scope

Report AttributeDetails
Revenue forecast in 2025USD 130.3 million by 2025
Growth Rate7.1% from 2018 to 2025
Forecast period2022 – 2030
Base year for estimation2021
Segments CoveredTechnique, End-use, Regional
Key Companies ProfiledGE Healthcare Lifesciences, Merck KGaA, Tosoh Corp, Purolite Corp, Danaher Corp, and Bio-Rad Labs
Market representationVolume in Thousand Liters; Revenue in USD Million, and CAGR from 2018 to 2025
Regional scopeNorth America, Europe, Asia Pacific
Country scopeU.S., U.K., Germany, France, China, India, Japan, South Korea.
Report coverageRevenue forecast, competitive landscape, growth factors and trends
Pricing and purchase optionsAvail customized purchase options to meet your exact research needs.  

Global Mixed Mode Chromatography Resin Market Segmentation

By Type
  • Ion Exchange-Hydrophobic Type
  • Hydroxyapatite Type
  • Others
By Application
  • Antibodies Production
  • Vaccine Production
  • Non-antibody Proteins
  • Antibody-drug conjugate
  • Separation of low molecular weight impurities

Key Market Players

  • Bio-Rad Laboratories
  • Bio-Works Company Ltd.
  • Danaher Corporation
  • GE Healthcare Life Sciences
  • Merck
  • Pall Corporation
  • Purolite Corporation
  • Sepragen Corporation
  • Thermo Fisher Scientific
  • Tosoh Corporation
  • JSR Micro Inc.
  • Kaneka Corporation
  • Knauer Gmbh
  • Life Technology Corporation
  • Others

Regional Outlook 

  • North America
    • US
    • Canada
    • Mexico
  • Europe
    • Germany
    • Italy
    • France
    • UK
    • Spain
    • Poland
    • Russia
    • The Netherlands
    • Norway
    • Czech Republic
    • Rest of Europe
  • Asia Pacific
    • China
    • Japan
    • India
    • South Korea
    • Indonesia
    • Malaysia
    • Thailand
    • Singapore
    • Australia & New Zealand
    • Rest of Asia Pacific
  • South America
    • Brazil
    • Argentina
    • Colombia
    • Rest of South America
  • The Middle East & Africa
    • Saudi Arabia
    • UAE
    • South Africa
    • Northern Africa
    • Rest of MEA

Table of content

Chapter 1 Methodology and Scope
                 1.1 Research methodology
                 1.2 Research scope and assumptions
                 1.3 List of data sources
                 1.4 List of abbreviations
Chapter 2 Executive Summary
                 2.1 Market snapshot
Chapter 3 Market Variables, Trends, and Scope
                 3.1 Market segmentation
                 3.2 Penetration & growth prospect mapping, 2014 – 2025
                 3.3 Value chain analysis
                 3.4 Regulatory framework
                 3.5 Technology overview
                 3.6 Market dynamics
                     3.6.1 Market driver analysis
                         3.6.1.1 High demand considering advances in drug development
                     3.6.2 Market restraint analysis
                         3.6.2.1 Costlier than other separation techniques
                 3.7 Industry analysis – Porter’s
                 3.8 PESTEL analysis
Chapter 4 Mixed Mode Chromatography Resin Market: Technique Estimates & Trend Analysis
                 4.1 Technique movement analysis, 2017 & 2025
                 4.2 Global Mixed Mode Chromatography Resin demand by technique, 2014 – 2025 (Thousand liters)
                     4.2.1 Mixed Mode Chromatography Resin market estimates & forecast, 2014 – 2025
                 4.3 Ion exchange – Hydrophobic
                     4.3.1 Ion exchange – Hydrophobic resin market estimates & forecast 2014 – 2025
                     4.3.2 Ion exchange – Hydrophobic resin estimates & forecast, by region, 2014 – 2025
                 4.4 Hydroxyapatite
                     4.4.1 Hydroxyapatite market estimates & forecast, 2014 – 2025
                     4.4.2 Hydroxyapatite resin market estimates & forecast, by region, 2014 – 2025
Chapter 5 Mixed Mode Chromatography Resin Market: End-Use Estimates & Trend Analysis
                 5.1 End-use movement analysis, 2017 & 2025
                 5.2 Global Mixed Mode Chromatography Resin demand, by end-use, 2014 – 2025 (Thousand litres) (USD Million)
                     5.2.1 Mixed Mode Chromatography Resin market estimates & forecast, 2014 – 2025
                     5.2.2 Pharmaceutical & Biotechnology market estimates & forecast, by region, 2014 – 2025
Chapter 6 Mixed Mode Chromatography Resin Market: Regional Estimates & Trend Analysis
                 6.1 Regional Market Introduction, 2017 & 2025
                 6.2 Global Mixed Mode Chromatography Resin demand, by region, 2014 – 2025 (Thousand litres) (USD Million)
                     6.2.1 Mixed Mode Chromatography Resin market estimates & forecast, 2014 – 2025
                 6.3 North America
                     6.3.1 Market estimates & forecast, 2014 – 2025
                     6.3.2 Market estimates & forecast, by technique, 2014 – 2025
                     6.3.3 Market estimates & forecast, By End Use, 2014 – 2025
                     6.3.4 U.S.
                         6.3.4.1 Market estimates & forecast, 2014 – 2025
                         6.3.4.2 Market estimates & forecast, by technique, 2014 – 2025
                         6.3.4.3 Market estimates & forecast, by end use, 2014 – 2025
                 6.4 Europe
                     6.4.1 Market estimates & forecast, 2014 – 2025
                     6.4.2 Market estimates & forecast, by technique, 2014 – 2025
                     6.4.3 Market estimates & forecast, by end use, 2014 – 2025
                     6.4.4 Germany
                         6.4.4.1 Market estimates & forecast, 2014 – 2025
                         6.4.4.2 Market estimates & forecast, by technique, 2014 – 2025
                         6.4.4.3 Market estimates & forecast, by end use, 2014 – 2025
                     6.4.5 France
                         6.4.5.1 Market estimates & forecast, 2014 – 2025
                         6.4.5.2 Market estimates & forecast, by technique, 2014 – 2025
                         6.4.5.3 Market estimates & forecast, by end use, 2014 – 2025
                     6.4.6 U.K.
                         6.4.6.1 Market estimates & forecast, 2014 – 2025
                         6.4.6.2 Market estimates & forecast, by technique, 2014 – 2025
                         6.4.6.3 Market estimates & forecast, by end use, 2014 – 2025
                 6.5 Asia Pacific
                     6.5.1 Market estimates & forecast, 2014 – 2025
                     6.5.2 Market estimates & forecast, by technique, 2014 – 2025
                     6.5.3 Market estimates & forecast, by end use, 2014 – 2025
                     6.5.4 China
                         6.5.4.1 Market estimates & forecast, 2014 – 2025
                         6.5.4.2 Market estimates & forecast, by technique, 2014 – 2025
                         6.5.4.3 Market estimates & forecast, by end use, 2014 – 2025
                     6.5.5 India
                         6.5.5.1 Market estimates & forecast, 2014 – 2025
                         6.5.5.2 Market estimates & forecast, by technique, 2014 – 2025
                         6.5.5.3 Market estimates & forecast, by end use, 2014 – 2025
                     6.5.6 Japan
                         6.5.6.1 Market estimates & forecast, 2014 – 2025
                         6.5.6.2 Market estimates & forecast, by technique, 2014 – 2025
                         6.5.6.3 Market estimates & forecast, by end use, 2014 – 2025
                     6.5.7 South Korea
                         6.5.7.1 Market estimates & forecast, 2014 – 2025
                         6.5.7.2 Market estimates & forecast, by technique, 2014 – 2025
                         6.5.7.3 Market estimates & forecast, by end use, 2014 – 2025
Chapter 7 Competitive Landscape
                 7.1 Vendor landscape
                 7.2 Competitive environment
                 7.3 Strategy framework
Chapter 8 Company Profiles
                 8.1 Merck KGaA
                     8.1.1 Company overview
                     8.1.2 Financial performance
                     8.1.3 Industries and services catered
                     8.1.4 Product benchmarking
                     8.1.5 Strategic initiatives
                 8.2 Bio-Rad Laboratories, Inc.
                     8.2.1 Company overview
                     8.2.2 Financial performance
                     8.2.3 Industries and services catered
                     8.2.4 Product benchmarking
                     8.2.5 Strategic initiatives
                 8.3 GE Healthcare
                     8.3.1 Company overview
                     8.3.2 Financial performance
                     8.3.3 Industries and services catered
                     8.3.4 Product benchmarking
                     8.3.5 Strategic initiatives
                 8.4 Puro-lite Corporation
                     8.4.1 Company overview
                     8.4.2 Financial performance
                     8.4.3 Industries and services catered
                     8.4.4 Product benchmarking
                     8.4.5 Strategic initiatives
                 8.5 Tosoh Corporation
                     8.5.1 Company overview
                     8.5.2 Financial performance
                     8.5.3 Industries and services catered
                     8.5.4 Product benchmarking
                     8.5.5 Strategic initiatives
                 8.6 Danaher Corporation
                     8.6.1 Company overview
                     8.6.2 Financial performance
                     8.6.3 Industries and services catered
                     8.6.4 Product benchmarking
                     8.6.5 Strategic initiatives
                 8.7 Avantor Performance Materials Inc.
                     8.7.1 Company overview
                     8.7.2 Financial performance
                     8.7.3 Industries and services catered
                     8.7.4 Product benchmarking
                     8.7.5 Strategic initiative

Segmentation

By Type
  • Ion Exchange-Hydrophobic Type
  • Hydroxyapatite Type
  • Others
By Application
  • Antibodies Production
  • Vaccine Production
  • Non-antibody Proteins
  • Antibody-drug conjugate
  • Separation of low molecular weight impurities

Companies

  • Bio-Rad Laboratories
  • Bio-Works Company Ltd.
  • Danaher Corporation
  • GE Healthcare Life Sciences
  • Merck
  • Pall Corporation
  • Purolite Corporation
  • Sepragen Corporation
  • Thermo Fisher Scientific
  • Tosoh Corporation
  • JSR Micro Inc.
  • Kaneka Corporation
  • Knauer Gmbh
  • Life Technology Corporation
  • Others

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